A new single guideline takes a 360-degree approach to managing heart disease in Canadian patients, with 83 recommendations in one easy-to-use reference. The guideline is published in the CMAJ Canadian Medical Association Journal. An update to a 2018 publication, the Canadian Cardiovascular Harmonized National Guideline Endeavor (C-CHANGE) resource includes 48 new or revised recommendations out of 83, from 11 cardiovascular-focused guideline groups across the country. Aimed at primary care and other health care providers, the C-CHANGE guideline contains recommendations for Canadian adults with or at risk of CVD, including those with obesity, diabetes or hypertension. people with dyslipidemia, atherosclerotic vascular disease or heart failure. and people with atrial fibrillation, stroke or dementia. It also includes health behavior recommendations for all Canadians to address risk factors for these conditions, such as diet, smoking and physical activity. Previously, more than 50% of the guideline contains new or revised recommendations from the previous version in 2018. This guideline is also more comprehensive and holistic in the care of patients with multimorbidity. Over the past 4 years, many of the national guideline organizations have initiated new evidence-based recommendations from changes in medication management to new thresholds for lipid levels in secondary prevention, we hope this resource helps primary care clinicians stay informed with many continually evolving cardiovascular guidelines so their patients can receive the best possible care, the researchers concluded. Report: New single guideline for cardiovascular health in Canada. CANADIAN MEDICAL ASSOCIATION JOURNAL, DOI:10.1503/cmaj.220138.